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Filtered Search Results
Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000744403 MPEG-AMINE MW 10000 250MG
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eMolecules 58794-09-5 | 7-Bromoisoquinoline | Oakwood Chemicals | MFCD07368661 | 208.058 | C9H6BrN | 0.000 | Brc1ccc2ccncc2c1 | 250mg | 480128099
7-Bromoisoquinoline | Oakwood Chemicals | 58794-09-5 | MFCD07368661 | 208.058 | C9H6BrN | 0.000 | Brc1ccc2ccncc2c1 | 250mg | 480128099
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000758686 UIO-66-BR 250MG
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eMolecules 4965-36-0 | 7-Bromoquinoline | ChemScene | MFCD03695823 | 208.058 | C9H6BrN | 96.000 | Brc1ccc2cccnc2c1 | 100g | 441676937
7-Bromoquinoline | ChemScene | 4965-36-0 | MFCD03695823 | 208.058 | C9H6BrN | 96.000 | Brc1ccc2cccnc2c1 | 100g | 441676937
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eMolecules 1255942-06-3 | DBCO-amine | Target Molecule | MFCD22380759 | 276.339 | C18H16N2O | 0.000 | NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 10mg | 662702332
DBCO-amine | Target Molecule | 1255942-06-3 | MFCD22380759 | 276.339 | C18H16N2O | 0.000 | NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 10mg | 662702332
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Sigma Aldrich Fine Chemicals Biosciences Mefloquine hydrochloride >=98% (HPLC), powder | 51773-92-3 | MFCD00797519 | 100MG
Mefloquine hydrochloride >=98% (HPLC), powder | Purity: >=98% (HPLC) | Mol Wt: 414.77 | 51773-92-3 | MFCD00797519 | 100MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000757524 SULFO-KMUS SODIUM S 50MG
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Medchemexpress LLC SB225002 | 182498-32-4 | 99.9% | 352.14 | 200 MG
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SB225002 | 182498-32-4 | 99.9% | 352.14 | 200 MG
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Medchemexpress LLC PVD-06 | 3032975-48-4 | 98.3% | 1074.13 | 1 MG
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PVD-06 is a selective PROTAC PTPN2 degrader with a DC50 of 217 nM. It induces PTPN2 degradation via a VHL-, ubiquitin, and proteasome-dependent pathway. PVD-06 can promote T cell activation and amplify IFN-γ-mediated anticancer activity, making it suitable for investigating PTPN2 in diseases such as leukemia and melanoma.
- Selective PROTAC PTPN2 degrader
- Induces PTPN2 degradation via VHL-, ubiquitin, and proteasome-dependent pathway
- Promotes T cell activation
- Amplifies IFN-γ-mediated anticancer activity
- Composed of a PTPN2 ligand, a linker, and a VHL ligand
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TARGETMOL CHEMICALS INC CPI-360 5MG
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502693842 CPI-360 5MG
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eMolecules 59107-51-6 | 8-CHLORONAPHTHALEN-1-AMINE | AstaTech | MFCD00465087 | 177.630 | C10H8ClN | 95.000 | Nc1cccc2cccc(Cl)c12 | 1g | 550782860
8-CHLORONAPHTHALEN-1-AMINE | AstaTech | 59107-51-6 | MFCD00465087 | 177.630 | C10H8ClN | 95.000 | Nc1cccc2cccc(Cl)c12 | 1g | 550782860
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eMolecules 343926-69-2 | 4-bromopyrimidin-2-amine | Pharmablock | MFCD09999168 | 174.001 | C4H4BrN3 | 97.000 | Nc1nccc(Br)n1 | 50g | 551064076
4-bromopyrimidin-2-amine | Pharmablock | 343926-69-2 | MFCD09999168 | 174.001 | C4H4BrN3 | 97.000 | Nc1nccc(Br)n1 | 50g | 551064076
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eMolecules 1612792-88-7 | potassium;[trans-2-ethoxycarbonylcyclopropyl]-trifluoro-boranuide | Pharmablock440.080 | C12H18B2F6K2O4 | 0.000 | [K+].[K+].CCOC(=O)[C@H]1C[C@@H]1[B-](F)(F)F.CCOC(=O)[C@@H]1C[C@H]1[B-](F)(F)F | 500mg | 812213422
potassium;[trans-2-ethoxycarbonylcyclopropyl]-trifluoro-boranuide | Pharmablock | 1612792-88-7440.080 | C12H18B2F6K2O4 | 0.000 | [K+].[K+].CCOC(=O)[C@H]1C[C@@H]1[B-](F)(F)F.CCOC(=O)[C@@H]1C[C@H]1[B-](F)(F)F | 500mg | 812213422
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eMolecules 103476-89-7 | Leupeptin Hemisulfate | TargetMol951.200 | C40H78N12O12S | 0.000 | OS(O)(=O)=O.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C=O.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C=O | 100mg | 812266535
Leupeptin Hemisulfate | TargetMol | 103476-89-7951.200 | C40H78N12O12S | 0.000 | OS(O)(=O)=O.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C=O.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C=O | 100mg | 812266535
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000745298 SN-38 200MG
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